The MEDPHOT Consortium

The International Photonics Translational Research – Medical Photonics

Publications

***These works are part of the research program Perspectief with project number P18-26, which is (partly) financed by the Dutch Research Council (NWO).***

Project 1

OCT Systems and catheter development combined with targeted fluorescence sensitivity, modelling of quantitative fluorescence
  • Vaselli M, Wijsman PC, Willemse J, Goorsenberg AWM, Feroldi F, d’Hooghe JNS, Annema JT, de Boer JF, Bonta PI. Polarization Sensitive Optical Coherence Tomography for Bronchoscopic Airway Smooth Muscle Detection in Bronchial Thermoplasty-Treated Patients With Asthma. Chest. 2021 Aug;160(2):432-435. doi: 10.1016/j.chest.2021.03.042. Epub 2021 Mar 27. PMID: 33785301; PMCID: PMC8411445.

In vivo polarisation sensitive optical coherence tomography for fibrosis assessment in interstitial lung disease: a prospective, exploratory, observational study
  • Vaselli M, Kalverda-Mooij K, Thunnissen E, et al. In vivo polarisation sensitive optical coherence tomography for fibrosis assessment in interstitial lung disease: a prospective, exploratory, observational study. BMJ Open Respir Res 2023;10:e001628. doi:10.1136/bmjresp-2023-001628

Ex vivo optical coherence tomography combined with near infrared targeted fluorescence: towards in-vivo esophageal cancer detection
  • Margherita Vaselli, Ruben Y. Gabriels, Iris Schmidt, Andrea J. Sterkenburg, Gursah Kats-Ugurlu, Wouter B. Nagengast, and Johannes F. de Boer. https://doi.org/10.1364/BOE.537828
Project 2
Structural and florescence imaging in lung cancer and asthma
  • [1] Vaselli M, Wijsman PC, Willemse J, Goorsenberg AWM, Feroldi F, d’Hooghe JNS, Annema JT, de Boer JF, Bonta PI. Polarization Sensitive Optical Coherence Tomography for Bronchoscopic Airway Smooth Muscle Detection in Bronchial Thermoplasty-Treated Patients With Asthma. Chest. 2021 Aug;160(2):432-435. doi: 10.1016/j.chest.2021.03.042. Epub 2021 Mar 27. PMID: 33785301; PMCID: PMC8411445. https://pubmed.ncbi.nlm.nih.gov/33785301
  • Kramer T, Wijsman PC, Kalverda KA, Bonta PI, Annema JT. Advances in bronchoscopic optical coherence tomography and confocal laser endomicroscopy in pulmonary diseases. Curr Opin Pulm Med. 2023;29(1):11-20
  • Vaselli M, Wijsman PC, Willemse J, Goorsenberg AWM, Feroldi F, d’Hooghe JNS, et al. Polarization sensitive optical coherence tomography (PS-OCT) for bronchoscopic airway smooth muscle detection in bronchial thermoplasty treated asthma patients. Chest. 2021
  • ERS 2021: Pieta Wijsman, et al. Optical coherence tomography detected changes in airway remodeling after bronchial thermoplasty in severe asthma. European Respiratory Journal 2021 58: OA231; DOI: 10.1183/13993003.congress-2021.OA231. Poster.
  • Kramer T, Annema JT. Advanced bronchoscopic techniques for the diagnosis and treatment of peripheral lung cancer. Lung Cancer. 2021;161:152-62.
  • Kramer T, Wijmans L, de Bruin M, van Leeuwen T, Radonic T, Bonta P, et al. Bronchoscopic needle-based confocal laser endomicroscopy (nCLE) as a real-time detection tool for peripheral lung cancer. Thorax. 2022;77(4):370-7.

In vivo polarisation sensitive optical coherence tomography for fibrosis assessment in interstitial lung disease: a prospective, exploratory, observational study
  • Vaselli M, Kalverda-Mooij K, Thunnissen E, et al. In vivo polarisation sensitive optical coherence tomography for fibrosis assessment in interstitial lung disease: a prospective, exploratory, observational study. BMJ Open Respir Res 2023;10:e001628. doi:10.1136/bmjresp-2023-001628
Project 3
Targeted near infrared florescence combined with OCT for eosphageal, colorectal and bile duct cancer imaging
Project 4
Novel Trans-Perineal Laser Ablation (TPLA) Platform for accurate treatment of prostate under MRI
Project 5
Optical Imaging of retinal manifestations of alizheimer’s disease for non-invasive diognosis
  • Hart de Ruyter FJ, Morrema THJ, den Haan J; Netherlands Brain Bank; Twisk JWR, de Boer JF, Scheltens P, Boon BDC, Thal DR, Rozemuller AJ, Verbraak FD, Bouwman FH, Hoozemans JJM. Phosphorylated tau in the retina correlates with tau pathology in the brain in Alzheimer’s disease and primary tauopathies. Acta Neuropathol. 2023 Feb;145(2):197-218. doi: 10.1007/s00401-022-02525-1.
Project 6
Targeted – fluorescence inspection of extracellular vesicles as liquid biopsy biomarkers for cancer
  • [1] Peters, A., Zhang, Z., & Faez, S. (2023, May 12). Dark-field light scattering microscope with focus stabilization. Nanophotonics, Debye Institute for Nanomaterials Science, Utrecht University, 3584CC Utrecht, The Netherlands. Ohx, e00424. https://doi.org/10.1016/j.ohx.2023.e00424.